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Exercise-associated hyponatremia, or EAH, is a fluid-electrolyte disorder caused by a decrease in sodium levels (hyponatremia) during or up to 24 hours after prolonged physical activity. This disorder can develop when marathon runners or endurance event athletes drink more fluid, usually water or sports drinks, than their kidneys can excrete. This excess water can severely dilute the level of sodium in the blood needed for organs, especially the brain, to function properly.〔 The incidence of EAH in athletes has increased in recent years, especially in the United States, as marathon races and endurance events have become more popular. A recent study showed 13% of the Boston 2002 marathon runners experienced EAH; most cases were mild.〔 Eight deaths from EAH have been documented since 1985.〔 ==Mechanism== Sodium is an important electrolyte needed for maintaining blood pressure. Sodium is mainly found in the body fluids that surround the cells and is necessary for nerves, muscles, and other body tissues to function properly.〔 Many factors may contribute to the development of EAH. Under normal conditions, sodium and water levels are regulated by the renal and hormonal systems.〔 The decrease in sodium levels can occur due to a defect in the renal and hormonal systems, an overwhelming increase in water consumption and excessive loss of sodium through sweating.〔 When the sodium levels outside of the cells decrease, water moves into the cells.〔 The cells begin to increase in size. When several cells in one area begin to increase in size, swelling occurs in the affected area. Swelling is commonly observed in hands, legs, and feet.〔 Sodium is also important in regulating the amount of water that passes through the blood-brain barrier. Decreased sodium blood levels result in increased permeability of water across the blood-brain barrier.〔Murray, B., Stofan, J., and Eichner, R. "SSE #88: Hyponatremia in Athletes." Gatorade Sports Science Institute. (2003).〕 This increased influx of water causes brain swelling which leads to severe neurological symptoms.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Exercise-associated hyponatremia」の詳細全文を読む スポンサード リンク
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